Frequently Asked Questions
Didn’t find an answer to your question? Post your question to our sbol-dev e-mailing list.
- Facilitates storage of genetic designs in repositories
- Helps synthetic biologists and genetic engineers electronically exchange designs with each other and with biofabrication centers
- Supports development of Genetic Design Automation (GDA) software tools for synthetic biologists
- Represents hierarchically assembled genetic compositions
- Represents abstract genetic compositions without an explicit nucleotide sequence
- Allows expression of genetic designs in publications and thus aids scientific reproducibility
- Captures elements of a design that move beyond DNA Sequences to include RNA, proteins, small molecules and molecular interactions
- SBOL is extensible to allow other kinds of data to be attached to the core data model. This includes, for example, experimental data, host information and mathematical models
- Introductory slides on SBOL can be found here
information for your paper in one file. You can also attach mathematical models to genetic designs SBOL will let you move your designs and work history between different tools.
We’d be very flattered if you wanted to use it, but if you like us that much, please consider donating or sponsoring
development of SBOL. We’d love to have you. Note, however, that use of the SBOL logo does not convey any kind of endorsement or certification
#EP/J02175X/1. Other sponsorship, support, or endorsements have been provided by the federal agencies, federal research centers,
commercial enterprises, and academic institutions. Please contact the SBOL Editors for donation consideration.
Genbank is a great file format for sequences and unstructured annotations. What can you do with SBOL that you can’t with Genbank? Genbank isn’t meant for designs. It will not represent interactions between components,
let you specify undefined components, is not modular and won’t describe designs using proteins and small molecules.
M. Lux, G. Misirli, J. Peccoud, H. Plahar, E. Sirin, G.B Stan, A. Villalobos, A. Wipat, J. Gennari, C. Myers, and H. Sauro. “The Synthetic Biology Open Language (SBOL) provides a community standard for communicating designs in synthetic biology,”
Nature Biotechnology, vol. 32, pp. 545-550, Jun. 2014. doi:10.1038/nbt.2891
N. Roehner, J. Beal, K. Clancy, B. Bartley, G. Misirli, R. Grunberg, E. Oberortner, M. Pocock, M. Bissell, C. Madsen, T. Nguyen, M. Zhang, Z. Zhang, Z. Zundel, D. Densmore, J. Gennari, A. Wipat, H. Sauro, and C. Myers. “Sharing structure and function
in biological design with SBOL 2.0,” ACS Synthetic Biology, vol. 5, no. 6, pp. 498-506, Apr. 2016. doi: 10.1021/acssynbio.5b00215
B. Bartley, J. Beal, K. Clancy, N. Hillson, G. Misirli, N. Roehner, H. Sauro, E. Oberortner, C. Madsen, M. Pocock, A. Wipat, T. Nguyen, Z. Zhang, C. Myers, J. Gennari, and M. Bissell. “Synthetic Biology Open Language (SBOL) Version 2.0.0,” Journal of Integrative Bioinformatics, vol.
12, no. 2, pp. 272, Sep. 2015. doi: 10.2390/biecoll-jib-2015-272..
and H. Sauro. “SBOL Visual: A Graphical Language for Genetic Designs,” PLoS Biol, vol. 13, no. 12, Dec. 2015.doi:10.1371/journal.pbio.1002310
no. 4, pp. 34-37, Mar. 2016. doi:10.1109/LLS.2016.2546546