2019 ACS Synthetic Biology Issues

Summary

  • Total Articles Analyzed: 287
  • Total Figures in All Articles: 1512
  • Figures Compatible with SBOL Visual: 432 (28.57%)
  • Figures Compatible with SBOL Visual & Fully Compliant: 219 (50.69%)
  • Figures Compatible with SBOL Visual & Following Best Practices: 126 (29.17%)

Individual issues

January

ArticleNo. of SBOL Visual compliant imagesNo. of SBOL Visual images following Best practices
Designing Spatially Distributed Gene Regulatory Networks To Elicit Contrasting Patterns10
Machine Learning of Designed Translational Control Allows Predictive Pathway Optimization in Escherichia coli22
Engineering the S-Layer of Caulobacter crescentus as a Foundation for Stable, High-Density, 2D Living Materials10
sboljs: Bringing the Synthetic Biology Open Language to the Web Browser22

February

ArticleNo. of SBOL Visual compliant imagesNo. of SBOL Visual images following Best practices
Riboswitch Signal Amplification by Controlling Plasmid Copy Number22
Building Microbial Hosts for Heterologous Production of N-Methylpyrrolinium20
A Regulatory NADH/NAD+ Redox Biosensor for Bacteria11
Chimeric LysR-Type Transcriptional Biosensors for Customizing Ligand Specificity Profiles toward Flavonoids70
CRISPR/Cas9-Based Genome Editing in the Filamentous Fungus Fusarium fujikuroi and Its Application in Strain Engineering for Gibberellic Acid Production22

March

ArticleNo. of SBOL Visual compliant imagesNo. of SBOL Visual images following Best practices
Characterizing Transcriptional Interference between Converging Genes in Bacteria44
Construction of a Nonnatural C60 Carotenoid Biosynthetic Pathway55
Synthetic Genome Defenses against Selfish DNA Elements Stabilize Engineered Bacteria against Evolutionary Failure77
An Artificial Biosynthetic Pathway for 2-Amino-1,3-Propanediol Production Using Metabolically Engineered Escherichia coli20
Metabolic Engineering of a Homoserine-Derived Non-Natural Pathway for the De NovoProduction of 1,3-Propanediol from Glucose40
Modulating Responses of Toehold Switches by an Inhibitory Hairpin20
Construction of Incoherent Feedforward Loop Circuits in a Cell-Free System and in Cells22

April

ArticleNo. of SBOL Visual compliant imagesNo. of SBOL Visual images following Best practices
Developing Riboswitch-Mediated Gene Regulatory Controls in Thermophilic Bacteria21
Spatiotemporal Gene Repression System in the Heterocyst-Forming Multicellular Cyanobacterium Anabaena sp. PCC 712022
Building an Inducible T7 RNA Polymerase/T7 Promoter Circuit in Synechocystis sp. PCC680341
Modeling Genetic Circuit Behavior in Transiently Transfected Mammalian Cells33
An Expanded Synthetic Biology Toolkit for Gene Expression Control in Acetobacteraceae60
Direct Aromatic Nitration System for Synthesis of Nitrotryptophans in Escherichia coli11
PLANT-Dx: A Molecular Diagnostic for Point-of-Use Detection of Plant Pathogens10
Rapid Assembly of gRNA Arrays via Modular Cloning in Yeast20

May

ArticleNo. of SBOL Visual compliant imagesNo. of SBOL Visual images following Best practices
Core Catalysis of the Reductive Glycine Pathway Demonstrated in Yeast10
Endocytosing Escherichia coli as a Whole-Cell Biocatalyst of Fatty Acids20
Genetic Incorporation of Noncanonical Amino Acids Using Two Mutually Orthogonal Quadruplet Codons10
Rapid, Heuristic Discovery and Design of Promoter Collections in Non-Model Microbes for Industrial Applications11

June

ArticleNo. of SBOL Visual compliant imagesNo. of SBOL Visual images following Best practices
Design and Evaluation of Synthetic Terminators for Regulating Mammalian Cell Transgene Expression10
Guiding Biomolecular Interactions in Cells Using de Novo Protein–Protein Interfaces50
Expanding the Isoprenoid Building Block Repertoire with an IPP Methyltransferase from Streptomyces monomycini10
Engineering Adenylate Cyclase Activated by Near-Infrared Window Light for Mammalian Optogenetic Applications21
Lessons from Two Design–Build–Test–Learn Cycles of Dodecanol Production in Escherichia coli Aided by Machine Learning33
Intracellular Noise Level Determines Ratio Control Strategy Confined by Speed–Accuracy Trade-off10
RiboCas: A Universal CRISPR-Based Editing Tool for Clostridium30
Development of a Genetically Encoded Biosensor for Detection of Polyketide Synthase Extender Units in Escherichia coli20
Engineered Reversal of Function in Glycolytic Yeast Promoters10
Characterization of a Panel of Strong Constitutive Promoters from Streptococcus thermophilus for Fine-Tuning Gene Expression10

July

ArticleNo. of SBOL Visual compliant imagesNo. of SBOL Visual images following Best practices
An Automated Biomodel Selection System (BMSS) for Gene Circuit Designs33
SBOL-OWL: An Ontological Approach for Formal and Semantic Representation of Synthetic Biology Information44
pySBOL: A Python Package for Genetic Design Automation and Standardization11
Specifying Combinatorial Designs with the Synthetic Biology Open Language (SBOL)22
A Computational Workflow for the Automated Generation of Models of Genetic Designs88
Design Principles for Compartmentalization and Spatial Organization of Synthetic Genetic Circuits10
An Engineered B. subtilis Inducible Promoter System with over 10 000-Fold Dynamic Range11

August

ArticleNo. of SBOL Visual compliant imagesNo. of SBOL Visual images following Best practices
Synthetic, Context-Dependent Microbial Consortium of Predator and Prey22
Inducible Gene Switches with Memory in Human T Cells for Cellular Immunotherapy44
Decorating the Outer Surface of Microbially Produced Protein Nanowires with Peptides20
Communicating Structure and Function in Synthetic Biology Diagrams77
Producing Gram-Scale Unnatural Rosavin Analogues from Glucose by Engineered Escherichia coli20

September

ArticleNo. of SBOL Visual compliant imagesNo. of SBOL Visual images following Best practices
Development of a Vanillate Biosensor for the Vanillin Biosynthesis Pathway in E. coli21
A Model for the Spatiotemporal Design of Gene Regulatory Circuits22
Spatiotemporal Dynamics of Synthetic Microbial Consortia in Microfluidic Devices10
Genome Engineering of Eubacterium limosum Using Expanded Genetic Tools and the CRISPR-Cas9 System11
Synthetic Biology Tools for the Fast-Growing Marine Bacterium Vibrio natriegens22
Quantification of Interlaboratory Cell-Free Protein Synthesis Variability11
ynthetic Gene Circuits Enable Escherichia coli To Use Endogenous H2S as a Signaling Molecule for Quorum Sensing55

October

ArticleNo. of SBOL Visual compliant imagesNo. of SBOL Visual images following Best practices
Low-Burden Biological Feedback Controllers for Near-Perfect Adaptation11
Amelioration of Diabetes in a Murine Model upon Transplantation of Pancreatic β-Cells with Optogenetic Control of Cyclic Adenosine Monophosphate11
Modular Thermal Control of Protein Dimerization33
SBOLExplorer: Data Infrastructure and Data Mining for Genetic Design Repositories22
Development of a Highly Sensitive Whole-Cell Biosensor for Arsenite Detection through Engineered Promoter Modifications11
Characterization and Engineering of a Clostridium Glycine Riboswitch and Its Use To Control a Novel Metabolic Pathway for 5-Aminolevulinic Acid Production in Escherichia coli10
Industrializing a Bacterial Strain for l-Serine Production through Translation Initiation Optimization43
An AND-Gated Drug and Photoactivatable Cre-loxP System for Spatiotemporal Control in Cell-Based Therapeutics40
Semisynthesis of the Neuroprotective Metabolite, Serofendic Acid33
Genetic Circuits To Detect Nanomaterial Triggered Toxicity through Engineered Heat Shock Response Mechanism21
Production of Phytochromes by High-Cell-Density E. coli Fermentation10

November

ArticleNo. of SBOL Visual compliant imagesNo. of SBOL Visual images following Best practices
Model-Driven Engineering of N-Linked Glycosylation in Chinese Hamster Ovary Cells22
In Vitro Transcriptional Regulation via Nucleic-Acid-Based Transcription Factors42

December

ArticleNo. of SBOL Visual compliant imagesNo. of SBOL Visual images following Best practices
Advancing CRISPR-Based Programmable Platforms beyond Genome Editing in Mammalian Cells10
Detecting Changes in the Caenorhabditis elegans Intestinal Environment Using an Engineered Bacterial Biosensor11
Seeded Chain-Growth Polymerization of Proteins in Living Bacterial Cells10
Pregnenolone Overproduction in Yarrowia lipolytica by Integrative Components Pairing of the Cytochrome P450scc System22
Switching the Ligand Specificity of the Biosensor XylS from meta to para-Toluic Acid through Directed Evolution Exploiting a Dual Selection System11
Engineering New Branches of the Kynurenine Pathway To Produce Oxo-(2-aminophenyl) and Quinoline Scaffolds in Yeast11
Organism Engineering for the Bioproduction of the Triaminotrinitrobenzene (TATB) Precursor Phloroglucinol (PG)11